Associate Professor

Bridgeside Point, 100 Technology Drive
Room 557, BRIDG
Pittsburgh, PA 15219-3130
Phone: (412) 624-5269
Email: lao1@pitt.edu

Personal Web Page

Research Interests
Publications
Education

Publications

• Boregowda S, Krishnappa V, Chambers J, Lograsso PV, Lai WT, Ortiz LA, Phinney DG.
  Atmospheric Oxygen Inhibits Growth and Differentiation of Marrow-Derived Mouse Mesenchymal Stem Cells Via a p53 Dependent Mechanism: Implications for Long-Term Culture Expansion.
  Stem Cells. 2012 Feb 24. doi: 10.1002/stem.1069. PMID:22367737
• Reed DS, Smith L, Dunsmore T, Trichel A, Ortiz LA, Cole KS, Barry E.
  Pneumonic tularemia in rabbits resembles the human disease as illustrated by radiographic and hematological changes after infection.
  PLoS One. 2011;6(9):e24654. Epub 2011 Sep 13. PMID: 21931798
• Martinu T, Palmer SM, Ortiz LA.
  Lung-resident mesenchymal stromal cells. A new player in post-transplant bronchiolitis obliterans syndrome?
  Am J Respir Crit Care Med. 2011 Apr 15;183(8):968-70. No abstract available.PMID: 21498820
• Di Giuseppe M, Gambelli F, Hoyle GW, Lungarella G, Studer SM, Richards T, Yousem S, McCurry K, Dauber J, Kaminski N, Leikauf G, Ortiz LA.
  Systemic inhibition of NF-kappaB activation protects from silicosis.
  PLoS ONE. 2009 May 25;4(5):e5689. PMID: 19479048
• Fattman CL, Torres G, Brockway BL, Stripp BR, Ortiz LA.
  Remodeling of the Respiratory Unit in Silica-exposed Mice. Proc Am Thorac Soc. 2008 Apr;5(3):375.
  No abstract available. PMID: 18403369
• Fattman CL, Gambelli F, Hoyle GW, Pitt BR, Ortiz LA
  Epithelial expression of TIMP1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice.
  Am J Physiol Lung Cell Mol Physiol. 2008 Jan 4; PMID: 18178676
• Reynolds, S.D*., Shen, H., Reynolds., PR., Betsuyaku, T., Pilewski, PM., Gambelli, F., DeGusippi, M., Ortiz , LA., B.R. Stripp.
  Molecular and Functional Properties of Lung Side Population Cells.
  *Corresponding author Am J Physiol Lung Cell Mol Physiol. 2007 Jan 12; PMID: 17142352
• Ortiz, L.A., Gambelli, F., Fatman, S., Pitt, B., and G.W. Hoyle.
  TIMP-1 expression contributes to mouse strain sensitivity to bleomycin: Implications for lung epithelial overexpression.
  Submitted.
• Ortiz, L.A., Fattman, C., Dutreil, M., and Phinney, D.
  Murine Mesenchymal stem cells block T-cell proliferation via production of Interleukin 1 receptor antagonist.
  In Revision (PNAS).

Education

Postgraduate Education:

• 1983-1984 Compulsory Social Service. Dispensario Beato Pampuri. La Esmeralda, Arauca, Colombia
• 1984-1987 Resident; Department of Internal Medicine Universidad Pontificia Bolivariana. Medellin, Colombia
• 1987-1990 Resident; Department of Internal Medicine Tulane Medical Center. New Orleans, Louisiana
• 1990-1993 Fellow; Pulmonary and Critical Care Medicine University of Texas Health Science Center and M.D. Anderson Cancer Center. Houston, Texas>/li>