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Back to topEOH - Graduate Training Program

EOH 1200 Introduction to Risk Assessment   Credits  3.0 Prerequisite: EOH 1200 This course will explore issues surrounding environmental and occupational risks with focus on adverse human health effect. It will provide an overview including risk assessment, risk perception, communications, and management.

EOH 2021 Special Studies  Credits  1.0 - 15.0 Properly qualified students may undertake advanced study under the guidance of a faculty member.

EOH 2101 Introduction to Research Methods I   Credits  1.0 Co-requisite: EOH 2102 This two semester course will introduce the basic skills required to conduct independent research in the health sciences. During the first semester emphasis will be placed on: critical review of literature, notebook keeping, exploratory data analysis, and use of the University library and database resources.

EOH 2102 Introduction to Research Methods II  Credits  1.0 Co-requisite: EOH 2101 This two semester course will introduce the basic skills required to conduct independent research in the health sciences. During the second semester emphasis will be placed on written and oral communication skills and development of research projects

EOH 2109 Molecular Toxicology Journal Club  Credits  1.0 This course is for students to gain experience in the presentation and discussion of topics of current interest in the fields of industrial and environmental health sciences and toxicology. The format is one hour weekly journal club presented by the students. Our goals are to expose students to the most exciting research our field of interest. Secondly, to provide a forum to hone skills in organizing and presenting scientific data, as well as critically discussing published work.

EOH 2110 Rotation Practicum   Credits  2.0 This course if designed to be a practical research experience for the PhD students. Students will gain research experience within laboratories of faculty within the Molecular Training Program. It will prepare students in the development of critical laboratory-based research skills including wet-lab, hands-on experimentation and literature-based research into specific areas of relevance.

EOH 2176 Principles of Toxicology Conference   Credits  2.0 Co-requisite: EOH 2175 This is a two credit course designed as an in-depth exploration of some the fundamental principles of toxicology. It is meant to accompany the material contained in the more didactic EOH 2175. Previous of concurrent enrollment in EOH 2175 is required for enrollment. It will also be of interest to any students interested in cellular and molecular aspects of toxicology. Its intent is to further explore a number of the concepts introduce in EOH 2175 at the molecular level and provide information critical to the practice of toxicology.

EOH 2301 Analytical Meth Molec Dosimetry   Credits  3.0 Prerequisite: EOH 2121 Principles and application of concentration, analysis and identification of xenobiotics, their metabolites and macro-molecular adducts at ultratrace level from biological matrice. Emphasis on methods which lead to identifying chemicals at molecular level, including gas, liquid and affinity chromatographies and various types mass spectrometry. Use of vibronic/electronic techniques such as raman and fluorescence spectroscopies, also discussed. Related methodology in literature which is current with each offering.

EOH 2302 Molecular approaches to Toxicology   Credits  2.0 This course is designed to introduce students to recent advances in field molecular toxicology. A basic foundation in genetics and tools of biotechnology will first be developed. Recent examples of innovation approaches used to study toxic agents at molecular level will then be described. Progress in the research of DNA/Protein adducts, xenobiotic metabolism and characterization of oncogenes will also be discussed.

EOH 2303 Applc Molec Biol Meth of Toxicology   Credits  2.0 Prerequisite: EOH 2302 This course is designed to introduce students to the techniques frequently used in a molecular biology laboratory, and to analyze and interpret data of experiments. This course will be taught as a series of lab training experiments and discussions.

EOH 2304 Biomarkers and Molecular Epid   Credits  2.0 Elective course summarized the concepts and biological principles underlying bases molecular biomarkers; provide students with understanding methodological principles of use; biomarkers epidemiologic research relevant to study of chronic human disease and public health application; summarize present use specific biomarkers in epidemiologic and clinical research with examples in human cancer, cardiovascular, immunological, and neurological diseases.

EOH 2305 Mechanisms DNA Metabolism and Damage Repair   Credits  3.0 Prerequisite: EOH 2317 Mechanisms and consequences of somatic and hereditary genetic damage, including method to detect characterize and quantify genetic lesions. The course provides molecular and theoretical basis for evaluation on genotoxicological data on exposure to mutagenetic/carcinogenic agents and on genetic predisposition or susceptibility to disease.

EOH 2306 Biochemical Techniques in Molecular Toxicology   Credits  2.0 The objectives of the course are to introduce EOH students to major instrumental biochemical laboratory techniques and to provide a foundation for understanding how specific problems in molecular toxicology can be experimentally addressed using biochemical methods. The course will be taught as a series of sessions including theoretical introduction, lab experiments and discussions.

EOH 2308 Model Systems   Credits  2.0 This course will examine how basic principles of cell and molecular biology can be applied to address problems in Environmental and Occupational Health. Students will gain an understanding of state of the art approaches to address problems in Environmental and Occupational Health through basic science research.

EOH 2310 Molecular Fundamentals   Credits  3.0 Course is designed to be a review of the fundamental of biochemistry, molecular biology, and cell biology. It will be taught in the first semester for PHD students and the first or third semester for MPH students. Students will be expected to have a solid undergraduate background in biology. There is significant time devoted to techniques, with the goal of providing background for PhD students beginning their research careers and a perspective for MPH students on the availability and utility of modern biological research methods.

EOH 2311 Molecular Fundamentals Conference   Credits  2.0 Co-requisite: EOH 2310 This course will consist of reviewing papers from top journals, each paper has been selected to illustrate topics covered in the lecture of the week. In addition to enhancing the understanding of material, the conference will teach students how to read and evaluate papers. Each student will be responsible for explaining all of the figures in the paper, one student per week will provide an introduction. It is required for EOH PhD students and open to PhD students in other disciplines. Master's level students will be admitted only with permission of instructor.

EOH 2312 Cellular Response to the Environment   Credits  3.0 The course is designed to introduce the concepts and basic principles of toxicant action as they relate to activation of cell-signaling mechanisms related to the development of human disease. The course is structured to provide didactic lectures on current understanding of mechanisms for responses to environmental toxicants and infectious agents, as well as discussion of cutting edge research discoveries.

EOH 2314 Pathophysiology of Environmental Diseases   Credits  3.0 This course is designed to be an overview of the fundamentals of Organ Systems Toxicology with an emphasis on mechanisms of cellular toxicology within the lung. A significant amount of time will be devoted to the cellular and biochemical aspects of tissue damage resulting form toxicant exposure. Student will gain skills in the areas of data analysis and presentation of work. Proposed.

EOH 2371 Cellular & Molecular Toxicology  Credits  2.0 The course is an introduction to cellular and molecular mechanisms in toxicology, designed to provide a foundation in chemical and macromolecular level events in cells exposed to chemical and physical agents. The cells response to these insults is examined from a mechanistic approach including mechanisms of recovery, repair and biochemical defenses. New techniques of molecular biology will be used to examine toxicological mechanisms.

EOH 2720 Applied Computational Toxicology 1  Credits  3.0 The course will introduce the principles and techniques of biomolecular modeling, including pharmacological and toxicological applications, Lectures will discuss pertinent aspects of chemistry, proteins and their ligands based on chemistry and physics; however, statistical modeling (Qsar Quantitative structure-activity relationships) will also be reviewed.

EOH 2725 Applied Computational Toxicology 2  Credits  3.0 Advanced modeling models such as expert systems, artificial neural networks, genetic algorithms and their application to toxicological quantitative structure activity relationships (QSAR) will be discussed. Advanced techniques in three-dimensional molecular modeling of small molecules, proteins and DNA will also be discussed. A series of lectures by recognized experts in each of the fields will be presented during the course.

EOH 2727 Cmptl Modeling Toxicological Research   Credits  3.0 Students are presented with the rationale and theory behind each of the model-building processes and are given out-of-class assignments to learn operational aspects. A project using data of the student’s choice contributes to the final grade.

EOH 3010 Research and Dissertation PhD  Credits  1.0 - 15.0 Dissertation credits for qualified Doctoral students in the Department of Environmental and Occupational Health.

EOH 3305 DNA Repair: Biochemistry to Human Disease  Credits  2.0 Cellular responses to DNA damage impact cell cycle control, transcription, replication, cell division, signal transduction and evolution.  More than 40 distinct human diseases are caused by defects in DNA repair including syndromes of impaired development, cancer predisposition or premature aging.  This course will emphasize the biochemistry of DNA repair, placing these mechanisms into the context of other cellular processes such as DNA replication, transcription and damage signaling.  Sources of DNA damage, both environmental and endogenous will be discussed, as well as the importance of DNA repair mechanisms during development and to prevent cancer and aging.  The course will follow the 2005 edition of the text DNA repair and mutagenesis, 2nd edition (ASM Press), co-authored by Dr. Richard D. Wood.  The format will include 1 hour of lecture per week based on selected material from the book and 1 hour of interactive discussion covering human disease, animal models, experimental systems to measure DNA damage and repair, and the latest literature.  Lecturers will include the faculty from the University of Pittsburgh who are engaged in laboratory research at the forefront of the DNA repair field. Several visiting special guest lecturers may also participate in the course.

FTDR 3999 Full-Time Dissertation Research  Credits  0 - 0 Doctoral Candidates who have completed all credit requirements for the degree, including any minimum dissertation requirements, and are working full-time on their dissertations may register for this course. While the course carries no credits and no grade, students who enroll in "Full-Time Dissertation Study" are considered by the University to have Full-Time registration status

Back to topEOH - MPH/DrPH

EOH 2013 Environmental Health and Disease   Credits  3.0 Cross listed with EOH 2012 Health, Disease, and Environment This is the Graduate School of Public Health core curriculum course in Environmental and Occupational Health. The discipline of Environmental and Occupational Health refers to the “theory and practice of assessing, correcting, controlling, and preventing those factors in the environment that can adversely affect the health of present and future generations.” This course will familiarize the student with current issues and practice in Environmental and Occupational Health, as well as assessment of risk of environmental exposures. It is designed to introduce the student to knowledge basic to public health focusing on chemical and physical environmental factors affecting the health of communities.

EOH 2022 Special Topics   Credits  1.0 - 3.0 Properly qualified students may undertake advanced study under the guidance of a faculty member

EOH 2104 Introduction to Envrl & Occ Health Law   Credits  3.0 This course is designed to introduce students to law as it relates to environmental disputes, including relevant occupational law. General overview of the structure and operation of the legal system, I.E., litigation. Majority of course will cover major federal and state statutes designed to protect the environment. Our study of these statutes will focus on the various approaches, strategies, standards and enforcement mechanisms. Coursework consists of lecture, reading and class discussion. There are no prerequisites.

EOH 2106 Environmental and Occupational Health Law   Credits  2.0 This course is designed to familiarize students with the legal aspects that govern environmental and occupational health at federal and state levels. Interpretation of the acts and laws by the courts is discussed by reference to specific cases.

EOH 2108 Environmental and Occupational Health Practicum   Credits  2.0 This practicum was designed to provide an opportunity for each EOH/Risk Assessment MPH student to demonstrate integration and application of knowledge in an area of environmental and occupational health through a culminating experience. The form of this experience is a faculty-supervised, applied research or problem solving project with a public health organization.

EOH 2122 Transport and Fate of Environmental Agents   Credits  3.0 Prerequisite: EOH 2309; EOH 2504 This course presents in a quantitative fashion the movement, transformation, bioaccumulation, and fate of various physical, biological and chemical agents throughout the environment, home and occupational settings. Chemical degradation, atmospheric transport, surface and groundwater sediments, and concentration by biological systems are described, including movement through food chains; also indoor transport and ventilation.

EOH 2175 Principles of Toxicology  Credits  3.0 Prerequisite: EOH 2309 This course will introduce students to the principles governing the interaction of chemicals within the human body. Major organ systems will be described with regard to anatomy, physiology and effects from interactions with chemical.

EOH 2180 Introduction to Risk Sciences  Credits  1.0 Prerequisite: EOH 2175 This course provides an overview of risk sciences including risk assessment, risk perception, risk communication and risk management. There is detailed attention to methods for qualitative and quantitative approaches to risk assessment for cancer and non-cancer health risks, using the four step paradigm developed by the National Academy of Sciences.

EOH 2181 Risk Assessment Practicum   Credits  2.0 Prerequisite: EOH 2180 The practicum provides the student with an opportunity to conduct a quantitative risk assessment for a human health endpoint (either cancer or non-cancer) from an environmental or occupational exposure. Students learn to identify human health hazards, assess dose response relationships, conduct an exposure assessment, and use that data to characterize risks to human health.

EOH 2309 Environmental Health Chemistry  Credits  3.0 The organic, inorganic and mechanistic biochemical details of interactions of toxins and biological systems will be presented. Emphasis on chemical understanding of potential toxicological sequelae of such interactions. Students present one lecture on bioorganic toxicological topic synthesized from recent scientific literature.

EOH 2313 Bioinorganic Chemistry in Public Health   Credits  2.0 Prerequisite: EOH 2309 The student will learn to think of biochemical processes in terms of properly balanced chemical equations, stressing the interdependency of many competing reactions. By the end of the course, it is expected that the student will confidently delve into much of the bioinorganic literature and be able to recognize when the authors of research papers have real insight rather than presenting tautological arguments.

EOH 2504 Principles of Environmental Exposure   Credits  3.0 This course induces concepts inherent in recognition of sources, contaminant generation, transport and uptake of chemical, biological and physical stresses in the context of potential environmental exposures related to human health. This course prepares students to understand exposure assessment in exposures related to human health. This course prepares students to understand exposure assessment in anticipation, recognition, evaluation and intervention as utilized in risk assessment and composition of matter, exposure pathways, pathway assessment methods including measurement, analogy and exposure mater modeling.

EOH 2513 Polc Dec Mkg PH Emrgy/Biotersm  Credits  3.0 This three-credit graduate course focuses on public health emergencies and bioterrorism at the phases of preparedness, mitigation, and response.  The course emphasizes not only biological agents but also all hazards with public health consequences.  It addresses the interfaces of policies and laws in the context of federalism, which requires interaction among the federal, state, and local levels of government.  The course considers the critical role of private-sector health care providers in addition to governmental decision makers.  Students explore past emergencies through history and case studies, conduct directed research on a chosen policy issue, and experience decision-making in the context of a simulated emergency by playing a chosen and previously research official role.  Teaching methods include lectures, case studies, policy research and writing, interdisciplinary classroom discussion, and simulated decision-making.  (The prerequisite is to be currently enrolled in a graduate or professional degree program, but this may be waived by the course director.)

EOH 2515 Environ & Occuptnl Health Preparedness   Credits  2.0 This course will be a graduate level course focusing on environmental health hazard with respect to disaster preparation, didactic and experimental aspects of course will include core principles of environmental health safety, Students will examine challenges with respect to natural and man-made disasters to allow student to prepare programs to handle environmental health emergencies.